Mercator MedSystems

The 15th and 16th Centuries marked the beginning of the Age of Exploration, a time of bold action, vast territorial expansion and profound intellectual discovery. Gerardus Mercator (1512-1594), a mathematician and cartographer, played a key role in these ventures. He was as important to navigation as Copernicus was to astronomy. He perfected a map projection that was the first to represent the spherical surface of the earth in two dimensions. The Mercator Projection effectively transformed navigation, making it possible for ships to deliver cargo safely to any port on the globe mercator medsystems

Inspired by the spirit of our namesake, Mercator MedSystems has developed a medical technology that enables the safe and accurate delivery of therapies anywhere in the body, ranging from drugs for diseased blood vessels, to stem cells that regenerate ailing tissues and organs. We believe this breakthrough will allow the expansion of medical therapy and stimulate profound intellectual exploration into new treatments for disease.

Mercator MedSystems, Inc., is a medical technology company focused on the treatment of peripheral artery disease using its catheter-guided, micro-infusion systems for site-specific, non-systemic delivery of therapeutic agents directly across any blood vessel. The company’s technology also enables therapies for vascular diseases, hypertension, oncology and regenerative medicine. The company’s Bullfrog® and Blowfish® Micro-Infusion Devices are the first systems able to infuse drugs, genes and cells safely through blood vessel or airway walls into deep tissues without major surgery.

The 15th and 16th Centuries marked the beginning of the Age of Exploration, a time of bold action, vast territorial expansion and profound intellectual discovery. Gerardus Mercator (1512-1594), a mathematician and cartographer, played a key role in these ventures. He was as important to navigation as Copernicus was to astronomy. He perfected a map projection that was the first to represent the spherical surface of the earth in two dimensions. The Mercator Projection effectively transformed navigation, making it possible for ships to deliver cargo safely to any port on the globe.

Inspired by the spirit of our namesake, Mercator MedSystems has developed a medical technology that enables the safe and accurate delivery of therapies anywhere in the body, ranging from drugs for diseased blood vessels, to stem cells that regenerate ailing tissues and organs. We believe this breakthrough will allow the expansion of medical therapy and stimulate profound intellectual exploration into new treatments for disease.

With a prevalence of approximately 27 million people in Europe and North America, peripheral artery disease (PAD) is a critical public health issue. Due to worldwide demographic changes towards an older population, the prevalence of PAD is likely to increase dramatically over the next 20 years.

The term PAD is used to refer to the obstruction of blood flow in the arteries, but does not include coronary or intracranial vessels.  PAD can result from atherosclerosis, embolism, thrombus formation or inflammatory processes leading to arterial stenosis or blockage. PAD is a major healthcare issue worldwide and patients with PAD have an increased risk of mortality, myocardial infarction and cerebrovascular disease. The predicted increase in the prevalence of PAD will intensify the demands placed on the healthcare services around the globe.

PAD therapies can include vessel bypass surgery or endovascular intervention: minimally invasive, catheter-based procedures that push or cut plaque out of the way so that normal blood flow can resume. Unfortunately, these endovascular procedures are plagued by inflammation and injury that leads to a buildup of new tissue similar to scar tissue. This can lead to re-obstruction, or restenosis, of the vessel. Local drug therapy has been shown valuable in the endovascular treatment of PAD with drug-eluting stents, drug-coated balloons, and the adventitial micro-infusion of drugs with the Bullfrog® device.