Before including a Vitamin B3 or niacin supplement in your routine, it’s advisable to consult your doctor, as recent research indicates that elevated levels of this essential B vitamin may pose a potential risk of heart disease. This discovery is noteworthy since this risk was not previously known.
However, it’s essential to clarify that there is no associated risk from the dietary intake of vitamin B3, naturally found in meat, fish, poultry, nuts, cereals, and bread. The recommended daily allowance for adult men is 16 milligrams, for women 14 milligrams, and up to 17 milligrams for mothers, easily attainable through a balanced diet. The identified risk appears to be linked to the prolonged use of prescribed Vitamin B3 supplements at around 1000 milligrams.
Why Do We Need Vitamin B3 or Niacin? Vitamin B3 aids the body in converting consumed foods into energy. The body does not store niacin, and any excess is excreted through urine.
Why is Vitamin B3 Used as a Supplement? For an extended period, it was utilized to address elevated levels of a harmful cholesterol known as Lipoprotein (A). This dense cholesterol, not typically indicated in a standard lipid profile test, serves as a significant indicator of cardiovascular health. Individuals with high levels of Lipoprotein (A) are at an increased risk of heart attack. While there is no specific medication for it, some doctors may prescribe vitamin B3, aiming for a modest reduction in Lipoprotein (A). This is particularly relevant for those with premature heart disease, a family history of it, familial hypercholesterolemia (FH), or recurrent cardiovascular events despite optimal LDL-lowering.
How Does Vitamin B3 Raise the Risk of Heart Attack? Recent research reveals that the breakdown products of niacin in the tested group led to inflammation. In an attempt to lower cholesterol, inflammation increased, narrowing arteries, accelerating plaque growth, damaging arterial walls, and potentially dislodging existing plaque. This tearing can cause clotting and blockages in the heart, triggering a heart attack.
What Should Those with Small Dense Cholesterol Do? Individuals with small dense cholesterol should rely on statins and aggressively manage lifestyle, diet, and exercise. Ongoing trials are exploring new therapeutic supplements to counteract the damaging end products of niacin. At present, multivitamin supplements are not deemed necessary.

















